Genecast CRC is our NGS-based test for multi-gene mutation detection of colorectal cancer.
Genecast CRC detects SNVs, Indels, fusions, CNVs and MSI. It also detects eight genes related to targeted therapy and one gene related to chemotherapy, and 70 simple sequence repeat (“SSR”) sites to determine MSI status in DNA extracted from FFPE tissue samples and ctDNA from liquid biopsy samples.
It combines genetic testing by sequencing the DNA or ctDNA with analysis against a proprietary database and algorithm, to determine gene mutations and provides the most effective targeted therapy or chemotherapy recommendation for the patient.
The table below summarizes the NCCN recommended colorectal cancer therapy guideline based on the detection of nine types of genetic mutations associated with colorectal cancer tested by Genecast CRC.